Retrotransposition of long interspersed nucleotide element-1 is associated with colitis but not tumors in a murine colitic cancer model.

Long interspersed element-1 (L1) is a transposable element that can move within the genome, potentially leading to genome diversity and modified gene function. Although L1 activity in somatic cells is normally suppressed through DNA methylation, some L1s are activated in tumors including colorectal...

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Principais autores:	Takeshi Otsubo, Tadashi Okamura, Teruki Hagiwara, Yukihito Ishizaka, Taeko Dohi, Yuki I Kawamura
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2015-01-01
coleção:	PLoS ONE
Acesso em linha:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0116072&type=printable
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