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Epigenetically upregulated NSUN2 confers ferroptosis resistance in endometrial cancer via m5C modification of SLC7A11 mRNA

Endometrial cancer (EC) is a prevalent gynecological malignancy worldwide, and 5-methylcytosine (m5C) modification of mRNA is a crucial epigenetic modification associated with the development and occurrence of several cancers. However, the precise function of m5C modification in EC remains elusive....

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Principais autores: Shuai-Jun Chen, Jun Zhang, Ting Zhou, Shan-Shan Rao, Qian Li, Ling-Yan Xiao, Si-Tian Wei, Hong-Feng Zhang
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2024-02-01
coleção:Redox Biology
Assuntos:
NSUN2
SLC7A11
m5C
Endometrial cancer
Ferroptosis
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2213231723003762
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