Introducing Pitt-Hopkins syndrome-associated mutations of TCF4 to Drosophila daughterless
Pitt-Hopkins syndrome (PTHS) is caused by haploinsufficiency of Transcription factor 4 (TCF4), one of the three human class I basic helix-loop-helix transcription factors called E-proteins. Drosophila has a single E-protein, Daughterless (Da), homologous to all three mammalian counterparts. Here we...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Company of Biologists
2015-12-01
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| Series: | Biology Open |
| Assuntos: | |
| Acceso en liña: | http://bio.biologists.org/content/4/12/1762 |
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