Loss of Ptpn11 (Shp2) drives satellite cells into quiescence

The equilibrium between proliferation and quiescence of myogenic progenitor and stem cells is tightly regulated to ensure appropriate skeletal muscle growth and repair. The non-receptor tyrosine phosphatase Ptpn11 (Shp2) is an important transducer of growth factor and cytokine signals. Here we combi...

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Principais autores:	Joscha Griger, Robin Schneider, Ines Lahmann, Verena Schöwel, Charles Keller, Simone Spuler, Marc Nazare, Carmen Birchmeier
Format:	Artigo
Jezik:	Inglês
Izdano:	eLife Sciences Publications Ltd 2017-05-01
Serija:	eLife
Teme:	Shp2 Ptpn11 satellite cells skeletal muscle repair skeletal muscle growth quiescence
Online dostop:	https://elifesciences.org/articles/21552
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