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TCEB2 promotes M2 polarization of macrophages in triple negative breast cancer by mediating ubiquitination degradation of Slit2 through recruiting NEDD4

Background: M2-polarized tumor-associated macrophage infiltration is a key risk factor for poor prognosis in triple-negative breast cancer (TNBC). This study investigated the role of transcription elongation factor B polypeptide 2 (TCEB2) in regulating M2 macrophage polarization during TNBC developm...

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Principais autores: Li Liu, Wang Xiao, Jie Zeng, Jianing Yi, Haoli Gong, Luyao Liu
פורמט: Artigo
שפה:Inglês
יצא לאור: Elsevier 2025-12-01
סדרה:Translational Oncology
נושאים:
Triple-negative breast cancer
M2 macrophage polarization
TCEB2
Ubiquitination
Slit2
גישה מקוונת:http://www.sciencedirect.com/science/article/pii/S1936523325002670
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