High-throughput discovery of novel small-molecule inhibitors of acid Ceramidase
Ceramide has a key role in the regulation of cellular senescence and apoptosis. As Ceramide levels are lowered by the action of acid ceramidase (AC), abnormally expressed in various cancers, the identification of AC inhibitors has attracted increasing interest. However, this finding has been mainly...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis Group
2023-12-01
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| Col·lecció: | Journal of Enzyme Inhibition and Medicinal Chemistry |
| Matèries: | |
| Accés en línia: | https://www.tandfonline.com/doi/10.1080/14756366.2022.2150183 |
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