Characterization of cerebrospinal fluid biomarkers associated with neurodegenerative diseases in healthy cynomolgus and rhesus macaque monkeys

Abstract Monkeys are becoming important translational models of neurodegenerative disease. To facilitate model development, we measured cerebrospinal fluid (CSF) concentrations of key biomarkers in healthy male and female cynomolgus and rhesus macaques. Amyloid beta (Aβ40, Aβ42), tau (total tau [t‐t...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Emma L. Robertson, Susan E. Boehnke, Natalia de M. Lyra e Silva, Brittney Armitage‐Brown, Andrew Winterborn, Douglas J. Cook, Fernanda G. De Felice, Douglas P. Munoz
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Wiley 2022-01-01
Serie:	Alzheimer’s & Dementia: Translational Research & Clinical Interventions
Soggetti:	Alzheimer's disease amyloid beta biomarkers cerebrospinal fluid cynomolgus macaque neurofilament light
Accesso online:	https://doi.org/10.1002/trc2.12289
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!