Characterization of cerebrospinal fluid biomarkers associated with neurodegenerative diseases in healthy cynomolgus and rhesus macaque monkeys

Abstract Monkeys are becoming important translational models of neurodegenerative disease. To facilitate model development, we measured cerebrospinal fluid (CSF) concentrations of key biomarkers in healthy male and female cynomolgus and rhesus macaques. Amyloid beta (Aβ40, Aβ42), tau (total tau [t‐t...

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Hlavní autoři:	Emma L. Robertson, Susan E. Boehnke, Natalia de M. Lyra e Silva, Brittney Armitage‐Brown, Andrew Winterborn, Douglas J. Cook, Fernanda G. De Felice, Douglas P. Munoz
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Wiley 2022-01-01
Edice:	Alzheimer’s & Dementia: Translational Research & Clinical Interventions
Témata:	Alzheimer's disease amyloid beta biomarkers cerebrospinal fluid cynomolgus macaque neurofilament light
On-line přístup:	https://doi.org/10.1002/trc2.12289
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