Relationship between<em>UGT1A1</em>gene polymorphisms and toxicity of irinotecan-based chemotherapy in colorectal cancer
Background and purpose: Uridine diphosphoglucu-ronosyl transferase 1A1 (UGT1A1) is an important enzyme for metabolism of irinotecan. The activity of UGT1A1 enzyme was significantly affected by the gene polymorphism. This study aimed to investigate the correlation of UGT1A1*28 and *6 gene polymorphis...
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| Principais autores: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Editorial Office of China Oncology
2014-07-01
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| Serier: | Zhongguo aizheng zazhi |
| Fag: | |
| Online adgang: | http://www.china-oncology.com/thesisDetails#10.3969/j.issn.1007-3969.2014.07.003 |
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