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Relationship between<em>UGT1A1</em>gene polymorphisms and toxicity of irinotecan-based chemotherapy in colorectal cancer

Background and purpose: Uridine diphosphoglucu-ronosyl transferase 1A1 (UGT1A1) is an important enzyme for metabolism of irinotecan. The activity of UGT1A1 enzyme was significantly affected by the gene polymorphism. This study aimed to investigate the correlation of UGT1A1*28 and *6 gene polymorphis...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: 周琰, 庄荣源, 陈朴, 谈绮文, 张春燕, 郭玮, 刘天舒, 潘柏申
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Editorial Office of China Oncology 2014-07-01
Sarja:Zhongguo aizheng zazhi
Aiheet:
Linkit:http://www.china-oncology.com/thesisDetails#10.3969/j.issn.1007-3969.2014.07.003
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