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Biological effects of selective COX-2 inhibitor NS398 on human glioblastoma cell lines

Abstract Background Cyclooxygenase-2 (COX-2), an inflammation-associated enzyme, has been implicated in tumorigenesis and progression of glioblastoma (GBM). The poor survival of GBM was mainly associated with the presence of glioma stem cells (GSC) and the markedly inflammatory microenvironment. To...

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Huvudupphov: Paola Palumbo, Francesca Lombardi, Francesca Rosaria Augello, Ilaria Giusti, Vincenza Dolo, Pietro Leocata, Maria Grazia Cifone, Benedetta Cinque
Materialtyp: Artigo
Språk:Inglês
Utgiven: BMC 2020-05-01
Serie:Cancer Cell International
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Länkar:http://link.springer.com/article/10.1186/s12935-020-01250-7
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