A Recombinant Zika Virus Envelope Protein with Mutations in the Conserved Fusion Loop Leads to Reduced Antibody Cross-Reactivity upon Vaccination

Zika virus (ZIKV) is a zoonotic, human pathogenic, and mosquito-borne flavivirus. Its distribution is rapidly growing worldwide. Several attempts to develop vaccines for ZIKV are currently ongoing. Central to most vaccination approaches against flavivirus infections is the envelope (E) protein, whic...

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Ngā kaituhi matua:	Beatrice Sarah Berneck, Alexandra Rockstroh, Jasmin Fertey, Thomas Grunwald, Sebastian Ulbert
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	MDPI AG 2020-10-01
Rangatū:	Vaccines
Ngā marau:	Zika virus E-protein fusion loop mutations vaccine dengue virus
Urunga tuihono:	https://www.mdpi.com/2076-393X/8/4/603
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!