Targeting the SPC25/RIOK1/MYH9 Axis to Overcome Tumor Stemness and Platinum Resistance in Epithelial Ovarian Cancer

Abstract In epithelial ovarian cancer (EOC), platinum resistance, potentially mediated by cancer stem cells (CSCs), often leads to relapse and treatment failure. Here, the role of spindle pole body component 25 (SPC25) as a key determinant promoting stemness and platinum resistance in EOC cells, wit...

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Үндсэн зохиолчид:	Xingyu Jiang, Muwen Yang, Weijing Zhang, Dongni Shi, Yue Li, Lixin He, Shumei Huang, Boyu Chen, Xuwei Chen, Lingzhi Kong, Yibing Pan, Pinwei Deng, Rui Wang, Ying Ouyang, Xiangfu Chen, Jun Li, Zheng Li, Hequn Zou, Yanna Zhang, Libing Song
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Wiley 2024-12-01
Цуврал:	Advanced Science
Нөхцлүүд:	cancer stem cell cell‐penetrating peptide epithelial ovarian cancer phosphorylation platinum resistance protein‐protein interaction
Онлайн хандалт:	https://doi.org/10.1002/advs.202406688
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!