Replication-driven HBV cccDNA loss in chimeric mice with humanized livers
ABSTRACT Hepatitis B virus (HBV) infection depends on the establishment of covalently closed circular DNA (cccDNA) and can be either transient or persistent. Persistent infection requires a noncytopathic viral phenotype, primarily achieved by limiting replication in infected cells. This study aimed...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2025-11-01
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| coleção: | Journal of Virology |
| Assuntos: | |
| Acesso em linha: | https://journals.asm.org/doi/10.1128/jvi.01295-25 |
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