Mesenchymal Stem Cell Secretome Attenuates PrP^106-126-Induced Neurotoxicity by Suppressing Neuroinflammation and Apoptosis and Enhances Cell Migration

Prion diseases are disorders caused by the misfolding of prion protein (PrP^Sc), leading to the accumulation of an abnormal form of the normal prion protein (PrP) found in the host. The secretome of mesenchymal stem cells (MSCs), including paracrine-soluble factors, holds promising potenti...

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Bibliografische Detailangaben

Hauptverfasser:	Mohammed Zayed, Byung-Hoon Jeong
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2025-06-01
Schriftenreihe:	Cells
Schlagworte:	mesenchymal stem cells prion disease PrP<sup>106−126</sup> apoptosis conditioned medium secretome
Online-Zugang:	https://www.mdpi.com/2073-4409/14/11/851
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