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Mesenchymal Stem Cell Secretome Attenuates PrP<sup>106-126</sup>-Induced Neurotoxicity by Suppressing Neuroinflammation and Apoptosis and Enhances Cell Migration

Prion diseases are disorders caused by the misfolding of prion protein (PrP<sup>Sc</sup>), leading to the accumulation of an abnormal form of the normal prion protein (PrP) found in the host. The secretome of mesenchymal stem cells (MSCs), including paracrine-soluble factors, holds promising potenti...

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Principais autores: Mohammed Zayed, Byung-Hoon Jeong
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2025-06-01
Serier:Cells
Fag:
mesenchymal stem cells
prion disease
PrP<sup>106−126</sup>
apoptosis
conditioned medium
secretome
Online adgang:https://www.mdpi.com/2073-4409/14/11/851
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