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Spray-dried cyclophosphamide-loaded polyhydroxyalkanoate microparticles: design and characterization

Background and purpose: Cyclophosphamide (CP) is a widely used antitumor and immunosuppressive drug, but it is highly cytotoxic and has carcinogenic and teratogenic potential. To reduce adverse effects of CP therapy and the frequency of its administration, the microencapsulation of CP into biodegra...

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Autors principals: Sergei Lipaikin, Aleksei Dorokhin, Galina Ryltseva, Andrey Oberenko, Evgeniy Kiselev, Alexander Shabanov, Tatiana Volova, Ekaterina Shishatskaya
Format: Artigo
Idioma:Inglês
Publicat: International Association of Physical Chemists (IAPC) 2024-10-01
Col·lecció:ADMET and DMPK
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Accés en línia:https://pub.iapchem.org/ojs/index.php/admet/article/view/2434
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