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Structural insights into the quinolone resistance mechanism of Mycobacterium tuberculosis DNA gyrase.

Mycobacterium tuberculosis DNA gyrase, an indispensable nanomachine involved in the regulation of DNA topology, is the only type II topoisomerase present in this organism and is hence the sole target for quinolone action, a crucial drug active against multidrug-resistant tuberculosis. To understand...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Jérémie Piton, Stéphanie Petrella, Marc Delarue, Gwénaëlle André-Leroux, Vincent Jarlier, Alexandra Aubry, Claudine Mayer
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Public Library of Science (PLoS) 2010-01-01
Rangatū:PLoS ONE
Urunga tuihono:http://europepmc.org/articles/PMC2923608?pdf=render
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