Excision of Nucleopolyhedrovirus Form Transgenic Silkworm Using the CRISPR/Cas9 System
The CRISPR/Cas9-mediated genome engineering has been shown to efficiently suppress infection by disrupting genes of the pathogen. We recently constructed transgenic lines expressing CRISPR/Cas9 and the double sgRNA target Bombyx mori nucleopolyhedrovirus (BmNPV) immediate early-1 (ie-1) gene in the...
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| Principais autores: | , , , , , , , , |
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| 格式: | Artigo |
| 语言: | Inglês |
| 出版: |
Frontiers Media S.A.
2018-02-01
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| 丛编: | Frontiers in Microbiology |
| 主题: | |
| 在线阅读: | http://journal.frontiersin.org/article/10.3389/fmicb.2018.00209/full |
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