Polystyrene microplastics disrupt osteogenic differentiation via lysosome-mediated mitochondrial dysfunction: Protective role of mTOR signaling

Polystyrene microplastics (PS-MPs), increasingly detected in aquatic environments, raise health concerns for humans and animals. However, their specific cellular effects remain incompletely characterized. This study identifies a mechanistic pathway by which PS-MPs impair osteogenic differentiation v...

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Autori principali:	Sobarathne Senel Sanjaya, Wisurumuni Arachchilage Hasitha Maduranga Karunarathne, Jinkuk Park, Cheng-Yun Jin, Yung Hyun Choi, Gi-Young Kim
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	KeAi Communications Co., Ltd. 2026-01-01
Serie:	Environmental Chemistry and Ecotoxicology
Soggetti:	Endocytosis Lysosomal stress Mitochondrial dysfunction Osteogenic differentiation Polystyrene microplastics
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2590182625002486
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