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Regulation of T Cell Trafficking by Enzymatic Synthesis of O-Glycans

Selectins constitute a family of oligosaccharide binding proteins that play critical roles in regulating the trafficking of leukocytes. In T cells, L-selectin (CD62L) controls the capacity for naive and memory T cells to actively survey peripheral lymph nodes, whereas P- and E-selectin capture activ...

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Autori principali: Samuel J. Hobbs, Jeffrey C. Nolz
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2017-05-01
Serie:Frontiers in Immunology
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Accesso online:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00600/full
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