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GlcNAc6ST2/CHST4 Is Essential for the Synthesis of R-10G-Reactive Keratan Sulfate/Sulfated <i>N</i>-Acetyllactosamine Oligosaccharides in Mouse Pleural Mesothelium

We recently showed that 6-sulfo sialyl <i>N</i>-acetyllactosamine (LacNAc) in <i>O</i>-linked glycans recognized by the CL40 antibody is abundant in the pleural mesothelium under physiological conditions and that these glycans undergo complementary synthesis by GlcNAc6ST2 (encoded by <i>Chst4</i>) a...

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Main Authors: Yoshiko Takeda-Uchimura, Midori Ikezaki, Tomoya O. Akama, Yoshito Ihara, Fabrice Allain, Kazuchika Nishitsuji, Kenji Uchimura
Format: Artigo
Language:Inglês
Published: MDPI AG 2024-02-01
Series:Molecules
Subjects:
sulfotransferase
keratan sulfate
sialomucin
mesothelium
MUC16
Online Access:https://www.mdpi.com/1420-3049/29/4/764
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