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Targeting the KAT8/YEATS4 Axis Represses Tumor Growth and Increases Cisplatin Sensitivity in Bladder Cancer

Abstract Bladder cancer (BC) is one of the most common tumors characterized by a high rate of relapse and a lack of targeted therapy. Here, YEATS domain‐containing protein 4 (YEATS4) is an essential gene for BC cell viability using CRISPR‐Cas9 library screening is reported, and that HUWE1 is an E3 l...

Whakaahuatanga katoa

I tiakina i:
Ngā kaituhi matua: Miner Xie, Liwen Zhou, Ting Li, Yujie Lin, Ruhua Zhang, Xianchong Zheng, Cuiling Zeng, Lisi Zheng, Li Zhong, Xiaodan Huang, Yezi Zou, Tiebang Kang, Yuanzhong Wu
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Wiley 2024-06-01
Rangatū:Advanced Science
Ngā marau:
KAT8
YEATS4
acetylation
bladder cancer
cisplatin sensitivity
DNA repair
Urunga tuihono:https://doi.org/10.1002/advs.202310146
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