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Targeting the KAT8/YEATS4 Axis Represses Tumor Growth and Increases Cisplatin Sensitivity in Bladder Cancer

Abstract Bladder cancer (BC) is one of the most common tumors characterized by a high rate of relapse and a lack of targeted therapy. Here, YEATS domain‐containing protein 4 (YEATS4) is an essential gene for BC cell viability using CRISPR‐Cas9 library screening is reported, and that HUWE1 is an E3 l...

Deskribapen osoa

Gorde:
Egile Nagusiak: Miner Xie, Liwen Zhou, Ting Li, Yujie Lin, Ruhua Zhang, Xianchong Zheng, Cuiling Zeng, Lisi Zheng, Li Zhong, Xiaodan Huang, Yezi Zou, Tiebang Kang, Yuanzhong Wu
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Wiley 2024-06-01
Saila:Advanced Science
Gaiak:
KAT8
YEATS4
acetylation
bladder cancer
cisplatin sensitivity
DNA repair
Sarrera elektronikoa:https://doi.org/10.1002/advs.202310146
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