SGK1 triggers cartilage degradation in TMJOA via FoxO1/autophagy

Abstract Background Temporomandibular joint osteoarthritis (TMJOA) is a prevalent inflammatory disease with unclear pathogenesis. Serum and glucocorticoid-inducible kinase 1 (SGK1) has been implicated in osteoarthritis-related cartilage degeneration. This study investigated the role of SGK1 in a mou...

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Bibliografski detalji

Glavni autori:	Hongyao Tang, Chuan Ma, Mengchen Xu, Gaoyi Wu, Na Li, Lei Chen
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2025-12-01
Serija:	Arthritis Research & Therapy
Teme:	Temporomandibular joint Condylar cartilage Chondrocyte Extracellular matrix Catabolism Anabolism
Online pristup:	https://doi.org/10.1186/s13075-025-03690-w
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