Preclinical biodistribution and safety evaluation of human iPSC-derived dopaminergic neural progenitor cells for Parkinson’s disease

IntroductionHuman pluripotent stem cells (PSCs) have the potential to revolutionize regenerative medicine, but their clinical safety has not been thoroughly investigated. We investigated the in vivo biodistribution, safety evaluation, and in situ tumorigenicity test of specific human iPSC-derived do...

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Principais autores:	Ying Huang, Hairuo Wen, Lily Li, Lulu Li, Qianqian Li, Chao Qin, Yiyang Mao, Zhi Lin, Hua Jiang, Frank Zhu, Xiang Li, Xingchao Geng
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2026-01-01
Colecção:	Frontiers in Cell and Developmental Biology
Assuntos:	biodistribution human iPSC-derived dopaminergic neural progenitor cells in vivo differentiation Parkinson’s disease safety evaluation study
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fcell.2025.1701748/full
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