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Repeat-dose toxicity study of human umbilical cord mesenchymal stem cells in cynomolgus monkeys by intravenous and subcutaneous injection

Human umbilical cord mesenchymal stem cells (hUC-MSCs) are proposed for the treatment of acute lung injury and atopic dermatitis. To advance hUC-MSC entry into clinical trials, the effects of hUC-MSCs on the general toxicity, immune perturbation and toxicokinetic study of hUC-MSCs in cynomolgus monk...

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Bibliografische gegevens
Hoofdauteurs: Wei Pan, Liqiang Gu, Hongzhong Yang, Cong Xu, Zhengbiao Yang, Qijiong Lu, Yuhua Shi, Lili Zhang, Jinjin Shao, Yunxiang Chen, Xin Pan, Feifei Wu, Ruolang Pan, Jinfeng Liang, Lijiang Zhang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2023-10-01
Reeks:Frontiers in Cell and Developmental Biology
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Online toegang:https://www.frontiersin.org/articles/10.3389/fcell.2023.1273723/full
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