Development of Droplet Digital PCR-Based Assays to Quantify HIV Proviral and Integrated DNA in Brain Tissues from Viremic Individuals with Encephalitis and Virally Suppressed Aviremic Individuals

ABSTRACT Although combination antiretroviral therapy (cART) can suppress the replication of HIV, the virus persists and rebounds when treatment is stopped. To find a cure that can eradicate latent reservoir, a method should be able to quantify the lingering HIV. Unlike other digital PCR technologies...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Hye Kyung Chung, Julian B. Hattler, Jigna Narola, Harita Babbar, Yanhui Cai, Mohamed Abdel-Mohsen, Woong-Ki Kim
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology 2022-02-01
coleção:	Microbiology Spectrum
Assuntos:	antiretroviral therapy brain droplet digital PCR HIV-1 HIV-associated neurocognitive disorders reservoir
Acesso em linha:	https://journals.asm.org/doi/10.1128/spectrum.00853-21
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!