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Development of Droplet Digital PCR-Based Assays to Quantify HIV Proviral and Integrated DNA in Brain Tissues from Viremic Individuals with Encephalitis and Virally Suppressed Aviremic Individuals

ABSTRACT Although combination antiretroviral therapy (cART) can suppress the replication of HIV, the virus persists and rebounds when treatment is stopped. To find a cure that can eradicate latent reservoir, a method should be able to quantify the lingering HIV. Unlike other digital PCR technologies...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Hye Kyung Chung, Julian B. Hattler, Jigna Narola, Harita Babbar, Yanhui Cai, Mohamed Abdel-Mohsen, Woong-Ki Kim
Hōputu: Artigo
Reo:Inglês
I whakaputaina: American Society for Microbiology 2022-02-01
Rangatū:Microbiology Spectrum
Ngā marau:
Urunga tuihono:https://journals.asm.org/doi/10.1128/spectrum.00853-21
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