A novel 3D bilayer hydrogel tri-culture system for studying functional motor units

Abstract Background A motor unit (MU) is formed by a single alpha motor neuron (MN) and the muscle fibers it innervates. The MU is essential for all voluntary movements. Functional deficits in the MU result in neuromuscular disorders (NMDs). The pathological mechanisms underlying most NMDs remain po...

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主要な著者:	Yu-Lung Lin, Jennifer Nhieu, Thomas Lerdall, Liming Milbauer, Chin-Wen Wei, Dong Jun Lee, Sang-Hyun Oh, Stanley Thayer, Li-Na Wei
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2023-09-01
シリーズ:	Cell & Bioscience
主題:	Motor unit Motor neuron Muscle Schwann cell Neuromuscular Hydrogel
オンライン･アクセス:	https://doi.org/10.1186/s13578-023-01115-2
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