A novel 3D bilayer hydrogel tri-culture system for studying functional motor units

Abstract Background A motor unit (MU) is formed by a single alpha motor neuron (MN) and the muscle fibers it innervates. The MU is essential for all voluntary movements. Functional deficits in the MU result in neuromuscular disorders (NMDs). The pathological mechanisms underlying most NMDs remain po...

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Autores principales:	Yu-Lung Lin, Jennifer Nhieu, Thomas Lerdall, Liming Milbauer, Chin-Wen Wei, Dong Jun Lee, Sang-Hyun Oh, Stanley Thayer, Li-Na Wei
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2023-09-01
Colección:	Cell & Bioscience
Materias:	Motor unit Motor neuron Muscle Schwann cell Neuromuscular Hydrogel
Acceso en línea:	https://doi.org/10.1186/s13578-023-01115-2
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