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Upregulated copper transporters in hypoxia-induced pulmonary hypertension.

Pulmonary vascular remodeling and increased arterial wall stiffness are two major causes for the elevated pulmonary vascular resistance and pulmonary arterial pressure in patients and animals with pulmonary hypertension. Cellular copper (Cu) plays an important role in angiogenesis and extracellular...

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Autori principali: Adriana M Zimnicka, Haiyang Tang, Qiang Guo, Frank K Kuhr, Myung-Jin Oh, Jun Wan, Jiwang Chen, Kimberly A Smith, Dustin R Fraidenburg, Moumita S R Choudhury, Irena Levitan, Roberto F Machado, Jack H Kaplan, Jason X-J Yuan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2014-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC3948681?pdf=render
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