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The effect of cephalexin in influencing the pharmacokinetics of a novel drug – 5′-valyl-cytarabine hydrochloride

The aim of this study is to investigate the pharmacokinetics of 5′-valyl-cytarabine hydrochloride (OPC) when co-administered with cephalexin, which are both the substrates of PepT1. The drugs were administered orally by gavage. Blood samples were collected from the orbital plexus of the rats after o...

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מידע ביבליוגרפי
Principais autores: Xiaotong Song, Yinghua Sun, Chenyao Zhao, Zhonggui He
פורמט: Artigo
שפה:Inglês
יצא לאור: KeAi Communications Co., Ltd. 2017-03-01
סדרה:Asian Journal of Pharmaceutical Sciences
נושאים:
גישה מקוונת:http://www.sciencedirect.com/science/article/pii/S1818087616300745
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