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The effect of cephalexin in influencing the pharmacokinetics of a novel drug – 5′-valyl-cytarabine hydrochloride

The aim of this study is to investigate the pharmacokinetics of 5′-valyl-cytarabine hydrochloride (OPC) when co-administered with cephalexin, which are both the substrates of PepT1. The drugs were administered orally by gavage. Blood samples were collected from the orbital plexus of the rats after o...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Xiaotong Song, Yinghua Sun, Chenyao Zhao, Zhonggui He
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: KeAi Communications Co., Ltd. 2017-03-01
Цуврал:Asian Journal of Pharmaceutical Sciences
Нөхцлүүд:
Онлайн хандалт:http://www.sciencedirect.com/science/article/pii/S1818087616300745
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