Optimized Ribociclib nanostructured lipid carrier for the amelioration of skin cancer: Inferences from ex-vivo skin permeation and dermatokinetic studies

Current research focuses on explicitly developing and evaluating nanostructured lipidic carriers (NLCs) for the chemotherapeutic drug Ribociclib (RCB) via the topical route to surmount the inherent bioavailability shortcomings. The absolute oral bioavailability has not been determined, but using a p...

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Detalhes bibliográficos

Principais autores:	Mohammed F. Aldawsari, Mohammad Azhar Kamal, Mohamed F. Balaha, Talha Jawaid, Mohammed Jafar, Sana Hashmi, Majid Ahmad Ganaie, Aftab Alam
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Springer 2024-03-01
Colecção:	Saudi Pharmaceutical Journal
Assuntos:	Ribociclib Nanostructured Lipidic Carriers BoxBehnken Design CLSM Dermatokinetics Skin cancer
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S1319016424000343
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