Optimized Ribociclib nanostructured lipid carrier for the amelioration of skin cancer: Inferences from ex-vivo skin permeation and dermatokinetic studies

Current research focuses on explicitly developing and evaluating nanostructured lipidic carriers (NLCs) for the chemotherapeutic drug Ribociclib (RCB) via the topical route to surmount the inherent bioavailability shortcomings. The absolute oral bioavailability has not been determined, but using a p...

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Autori principali:	Mohammed F. Aldawsari, Mohammad Azhar Kamal, Mohamed F. Balaha, Talha Jawaid, Mohammed Jafar, Sana Hashmi, Majid Ahmad Ganaie, Aftab Alam
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Springer 2024-03-01
Serie:	Saudi Pharmaceutical Journal
Soggetti:	Ribociclib Nanostructured Lipidic Carriers BoxBehnken Design CLSM Dermatokinetics Skin cancer
Accesso online:	http://www.sciencedirect.com/science/article/pii/S1319016424000343
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