PIP2 inhibits pore opening of the cyclic nucleotide-gated channel SthK
Abstract The signaling lipid phosphatidylinositol-4,5-bisphosphate (PIP2) regulates many ion channels. It inhibits eukaryotic cyclic nucleotide-gated (CNG) channels while activating their relatives, the hyperpolarization-activated and cyclic nucleotide-modulated (HCN) channels. The prokaryotic SthK...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Portfolio
2024-09-01
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| Serie: | Nature Communications |
| Accesso online: | https://doi.org/10.1038/s41467-024-52469-1 |
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