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Experimental Study of Almonertinib Crossing the Blood-Brain Barrier in EGFR-Mutant NSCLC Brain Metastasis and Spinal Cord Metastasis Models

Roughly one third of non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI)-sensitive mutated (EGFRm) tumors experience disease progression through central nervous system (CNS) metastases during treatment. Although EGFR-TKIs have been r...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Yuhan Zhang, Yaoshuai Zhang, Wenwen Niu, Xianming Ge, Fuhao Huang, Jinlong Pang, Xian Li, Yu Wang, Wei Gao, Fangtian Fan, Shanshan Li, Hao Liu
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2021-09-01
Rangatū:Frontiers in Pharmacology
Ngā marau:
Urunga tuihono:https://www.frontiersin.org/articles/10.3389/fphar.2021.750031/full
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