Effectiveness of Iptacopan Versus C5 Inhibitors in Complement Inhibitor‐Naive Patients With Paroxysmal Nocturnal Haemoglobinuria

ABSTRACT Background Paroxysmal nocturnal haemoglobinuria (PNH) is characterised by haemolytic anaemia, bone marrow failure and thrombosis. The single‐arm phase 3 APPOINT‐PNH trial (NCT04820530) investigating iptacopan monotherapy in complement inhibitor‐naive patients demonstrated significant haemog...

Volledige beschrijving

Bibliografische gegevens

Hoofdauteurs:	Matthew Holt, Richard J. Kelly, Jilles M. Fermont, Soudeh Ansari, Marion Dahlke, Isabelle Brindel, Lynda Maafa, Flore Sicre deFontbrune, Régis Peffault deLatour
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Wiley 2025-06-01
Reeks:	eJHaem
Onderwerpen:	APPEX APPOINT‐PNH C5 inhibitors iptacopan paroxysmal nocturnal haemoglobinuria
Online toegang:	https://doi.org/10.1002/jha2.70055
Tags:	Voeg label toe Geen labels, Wees de eerste die dit record labelt!