SPTBN2 suppresses ferroptosis in NSCLC cells by facilitating SLC7A11 membrane trafficking and localization

The function of SLC7A11 in the process of ferroptosis is well-established, as it regulates the synthesis of glutathione (GSH), thereby influencing tumor development along with drug resistance in non-small cell lung cancer (NSCLC). However, the determinants governing SLC7A11's membrane trafficking an...

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Detalhes bibliográficos

Principais autores:	Jun Deng, Xu Lin, Jiajia Qin, Qi Li, Yingqiong Zhang, Qingyi Zhang, Cong Ji, Shuying Shen, Yangling Li, Bo Zhang, Nengming Lin
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-04-01
Colecção:	Redox Biology
Assuntos:	SPTBN2 Ferroptosis NSCLC SLC7A11 membrane trafficking
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2213231724000156
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