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Characterization of Stimulatory Action on Voltage-Gated Na<sup>+</sup> Currents Caused by Omecamtiv Mecarbil, Known to Be a Myosin Activator

Omecamtiv mecarbil (OM, CK-1827452) is recognized as an activator of myosin and has been demonstrated to be beneficial for the treatment of systolic heart failure. However, the mechanisms by which this compound interacts with ionic currents in electrically excitable cells remain largely unknown. The...

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Bibliografiske detaljer
Principais autores: Chih-Yu Ting, Chia-Lung Shih, Meng-Cheng Yu, Chao-Liang Wu, Sheng-Nan Wu
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-05-01
Serier:Biomedicines
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Online adgang:https://www.mdpi.com/2227-9059/11/5/1351
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