DRhoGEF2 regulates cellular tension and cell pulsations in the Amnioserosa during Drosophila dorsal closure.

Coordination of apical constriction in epithelial sheets is a fundamental process during embryogenesis. Here, we show that DRhoGEF2 is a key regulator of apical pulsation and constriction of amnioserosal cells during Drosophila dorsal closure. Amnioserosal cells mutant for DRhoGEF2 exhibit a consist...

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Autores principales:	Dulce Azevedo, Marco Antunes, Soren Prag, Xiaoyan Ma, Udo Hacker, G Wayne Brodland, M Shane Hutson, Jerome Solon, Antonio Jacinto
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Public Library of Science (PLoS) 2011-01-01
Colección:	PLoS ONE
Acceso en línea:	http://europepmc.org/articles/PMC3174941?pdf=render
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