MDM2 Influences ACE2 Stability and SARS-CoV-2 Uptake

Angiotensin-converting enzyme 2 (ACE2) is the central entry receptor for SARS-CoV-2. However, surprisingly little is known about the effects of host regulators on ACE2 localization, expression, and the associated influence on SARS-CoV-2 infection. Here we identify that ACE2 expression levels are reg...

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Principais autores:	Quirin Emslander, Karsten Krey, Sabri Hamad, Susanne Maidl, Lila Oubraham, Joshua Hesse, Alexander Henrici, Katharina Austen, Julia Mergner, Vincent Grass, Andreas Pichlmair
格式:	Artigo
語言:	Inglês
出版:	MDPI AG 2023-08-01
叢編:	Viruses
主題:	severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) SARS-CoV-2 uptake MDM2 angiotensin-converting enzyme 2 (ACE2) ubiquitination
在線閱讀:	https://www.mdpi.com/1999-4915/15/8/1763
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