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Antibody fragments directed against different portions of the human neural cell adhesion molecule L1 act as inhibitors or activators of L1 function.

The neural cell adhesion molecule L1 plays important roles in neuronal migration and survival, neuritogenesis and synaptogenesis. L1 has also been found in tumors of different origins, with levels of L1 expression correlating positively with the metastatic potential of tumors. To select antibodies t...

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Detalhes bibliográficos
Principais autores: Yan Wang, Gabriele Loers, Hong-Chao Pan, Ricardo Gouveia, Wei-Jiang Zhao, Yan-Qin Shen, Ralf Kleene, Julia Costa, Melitta Schachner
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2012-01-01
coleção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3525558?pdf=render
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