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Mice Mutated in the First Fibronectin Domain of Adhesion Molecule L1 Show Brain Malformations and Behavioral Abnormalities

The X-chromosome-linked cell adhesion molecule L1 (L1CAM), a glycoprotein mainly expressed by neurons in the central and peripheral nervous systems, has been implicated in many neural processes, including neuronal migration and survival, neuritogenesis, synapse formation, synaptic plasticity and reg...

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Principais autores: Viviana Granato, Ludovica Congiu, Igor Jakovcevski, Ralf Kleene, Benjamin Schwindenhammer, Luciana Fernandes, Sandra Freitag, Melitta Schachner, Gabriele Loers
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2024-04-01
coleção:Biomolecules
Assuntos:
L1CAM
mutation
locomotion
open field
social interactions
circadian rhythm
Acesso em linha:https://www.mdpi.com/2218-273X/14/4/468
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