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Multi-omic analysis of SDHB-deficient pheochromocytomas and paragangliomas identifies metastasis and treatment-related molecular profiles

Abstract Hereditary SDHB-mutant pheochromocytomas (PC) and paragangliomas (PG) are rare tumours with a high propensity to metastasize although their clinical behaviour is unpredictable. To characterize the genomic landscape of these tumours and identify metastasis biomarkers, we perform multi-omic a...

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Detaylı Bibliyografya
Asıl Yazarlar: Aidan Flynn, Andrew D. Pattison, Shiva Balachander, Emma Boehm, Blake Bowen, Trisha Dwight, Fernando J. Rossello, Oliver Hofmann, Luciano Martelotto, Maia Zethoven, Lawrence S. Kirschner, Tobias Else, Lauren Fishbein, Anthony J. Gill, Arthur S. Tischler, Thomas Giordano, Tamara Prodanov, Jane R. Noble, Roger R. Reddel, Alison H. Trainer, Hans Kumar Ghayee, Isabelle Bourdeau, Marianne Elston, Diana Ishak, Joanne Ngeow Yuen Yie, Rodney J. Hicks, Joakim Crona, Tobias Åkerström, Peter Stålberg, Patricia Dahia, Sean Grimmond, Roderick Clifton-Bligh, Karel Pacak, Richard W. Tothill
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Portfolio 2025-03-01
Seri Bilgileri:Nature Communications
Online Erişim:https://doi.org/10.1038/s41467-025-57595-y
Etiketler: Etiketle
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