Dual-Target Compounds against Type 2 <i>Diabetes Mellitus</i>: Proof of Concept for Sodium Dependent Glucose Transporter (SGLT) and Glycogen Phosphorylase (GP) Inhibitors

A current trend in the quest for new therapies for complex, multifactorial diseases, such as diabetes mellitus (DM), is to find dual or even multi-target inhibitors. In DM, the sodium dependent glucose cotransporter 2 (SGLT2) in the kidneys and the glycogen phosphorylase (GP) in the liver are valida...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Ádám Sipos, Eszter Szennyes, Nikolett Éva Hajnal, Sándor Kun, Katalin E. Szabó, Karen Uray, László Somsák, Tibor Docsa, Éva Bokor
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2021-04-01
Schriftenreihe:	Pharmaceuticals
Schlagworte:	<i>C</i>-glucosyl heterocycle imidazole thiazole 1,2,3- and 1,2,4-triazole 1,2,4- and 1,3,4-oxadiazole pyrimidine
Online-Zugang:	https://www.mdpi.com/1424-8247/14/4/364
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