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Probing the functional mechanism of Escherichia coli GroEL using circular permutation.

BACKGROUND: The Escherichia coli chaperonin GroEL subunit consists of three domains linked via two hinge regions, and each domain is responsible for a specific role in the functional mechanism. Here, we have used circular permutation to study the structural and functional characteristics of the GroE...

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Autors principals: Tomohiro Mizobata, Tatsuya Uemura, Kazuhiro Isaji, Takuma Hirayama, Kunihiro Hongo, Yasushi Kawata
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2011-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC3196576?pdf=render
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