Comparative efficacy and safety of tissue plasminogen activators (tPA) in acute ischemic stroke: A systematic review and network meta-analysis of randomized controlled trials

Background: Intravenous alteplase (ALT) is the standard treatment for acute ischemic stroke (AIS). However, recent trials comparing other tissue plasminogen activators (tPAs) like tenecteplase (TNK) and reteplase with ALT have yielded conflicting results. This necessitated a network meta-analysis to...

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Ngā kaituhi matua:	Sufyan Shahid, MBBS, Humza Saeed, MBBS, Minahil Iqbal, MBBS, Ayesha Batool, MBBS, Muhammad Bilal Masood, MBBS, Muhammad Husnain Ahmad, MD, Aqeeb Ur Rehman, MD, Muhammad Aemaz Ur Rehman, MD, Fahd Sultan, MD
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Elsevier 2025-03-01
Rangatū:	Journal of Stroke and Cerebrovascular Diseases
Ngā marau:	Acute ischemic stroke Tissue plasminogen activator Alteplase Tenecteplase Reteplase Network meta-analysis
Urunga tuihono:	http://www.sciencedirect.com/science/article/pii/S1052305725000096
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