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Reversibility of β-Cell-Specific Transcript Factors Expression by Long-Term Caloric Restriction in db/db Mouse

Type 2 diabetes (T2D) is characterized by β-cell dedifferentiation, but underlying mechanisms remain unclear. The purpose of the current study was to explore the mechanisms of β-cell dedifferentiation with and without long-term control of calorie intake. We used a diabetes mouse model (db/db) to ana...

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Autores principales: Chunjun Sheng, Feng Li, Ziwei Lin, Manna Zhang, Peng Yang, Le Bu, Hui Sheng, Hong Li, Shen Qu
Formato: Artigo
Lenguaje:Inglês
Publicado: Wiley 2016-01-01
Colección:Journal of Diabetes Research
Acceso en línea:http://dx.doi.org/10.1155/2016/6035046
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